Herbal preparations and nutritional supplements may interact unfavorably with pharmaceutical drugs. For instance, some nutritional supplements recommended for nervous system function may not be recommended for those taking pharmaceutical antidepressants, such as taking 5-HTP, a nutritional supplement for the brain, or the herb St. John's Wort, with prescription antidepressants. Vitamin C should not be taken with aspirin, as it can irritate the stomach and limit absorption. Minerals should be taken in proper proportions to prevent unfavorable interactions; large amounts of zinc may deplete the body of the mineral copper, while too much calcium adversely affects the magnesium levels in the body. Balanced mineral supplements are recommended to alleviate these interactions.
Among general reasons for the possible harmful effects of dietary supplements are: a) absorption in a short time, b) manufacturing quality and contamination, and c) enhancing both positive and negative effects at the same time. The incidence of liver injury from herbal and dietary supplements is about 16–20% of all supplement products causing injury, with the occurrence growing globally over the early 21st century. The most common liver injuries from weight loss and bodybuilding supplements involve hepatocellular damage with resulting jaundice, and the most common supplement ingredients attributed to these injuries are green tea catechins, anabolic steroids, and the herbal extract, aegeline. Weight loss supplements have also had adverse psychiatric effects.
Everyone seems to have food allergies these days, but in fact, such allergies are rare. According to the National Institute of Allergy and Infectious Diseases, while one in three adults think they have a food allergy or modify their family's diet, only about four percent do. A food allergy is an abnormal immune-system response to certain foods (most commonly, fish, shellfish, peanuts, other nuts and eggs). Symptoms can include hives, rashes, nasal congestion, nausea, diarrhea and gas. However, symptoms of food intolerance—such as intestinal distress—may mimic those of a food allergy. You may want to talk to an allergist about diagnosis and treatment. Whether you have food allergies or intolerance, you will need to develop a diet that fits your needs and avoids foods that trigger a reaction.
"Staying well-hydrated helps your body function properly, and it also helps make sure you don’t overeat," Pam Bede, M.S., R.D. with Abbott’s EAS Sports Nutrition, tells SELF. But it's not just that staying hydrated keeps you from overeating. According to Maxine Yeung, M.S., R.D., owner of The Wellness Whisk, sometimes you may feel hungry when, in fact, you're actually thirsty. Basically, no harm can come from drinking a glass of water.
The soil in areas with relatively low rainfall may in some cases contain an extremely high concentration of minerals, which is reflected in the plants growing there. This was well documented 70 years ago in the book Tomorrow's Food.  The Dentist George W. Heard found that the soil in Hereford, Texas, was exceptionally rich in minerals. Hereford became known as the "town without a toothache" after a newspaper article from January 29, 1942, reported that Hereford had the lowest incidence of tooth decay of any city in the United States.  Heard found that people in Hereford had exceptionally few dental cavities and also that the soil locally was especially rich in minerals. He emphasized that the population in the county ate unprocessed food and was drinking raw milk. 
In the United States, the Dietary Supplement Health and Education Act of 1994 provides this description: "The Dietary Supplement Health and Education Act of 1994 (DSHEA) defines the term “dietary supplement” to mean a product (other than tobacco) intended to supplement the diet that bears or contains one or more of the following dietary ingredients: a vitamin, a mineral, an herb or other botanical, an amino acid, a dietary substance for use by man to supplement the diet by increasing the total dietary intake, or a concentrate, metabolite, constituent, extract, or combination of any of the aforementioned ingredients. Furthermore, a dietary supplement must be labeled as a dietary supplement and be intended for ingestion and must not be represented for use as conventional food or as a sole item of a meal or of the diet. In addition, a dietary supplement cannot be approved or authorized for investigation as a new drug, antibiotic, or biologic, unless it was marketed as a food or a dietary supplement before such approval or authorization. Under DSHEA, dietary supplements are deemed to be food, except for purposes of the drug definition."
Dietary supplements are complex products. The FDA has established good manufacturing practices (GMPs) for dietary supplements to help ensure their identity, purity, strength, and composition. These GMPs are designed to prevent the inclusion of the wrong ingredient, the addition of too much or too little of an ingredient, the possibility of contamination, and the improper packaging and labeling of a product. The FDA periodically inspects facilities that manufacture dietary supplements.