A spokesperson for optimal nutritional intake is the well-known biochemist Bruce Ames, who proposed the "triage theory of nutrients," in which enzymes responsible for cell maintenance functions evolved to have lower affinity for the essential vitamin and mineral cofactors than the enzymes responsible for short-term survival, to preserve life during times of famine. 
Guess what? I eat pizza and fried chicken and cheesecake and doughnuts and I drink coke and coffee and all those greasy, fatty, high-carb, unhealthy foods. BUT I eat them only on cheat days at most once a week. What’s a cheat day? Well, every week, I set aside one day where I allow myself to enjoy the foods I used to love before starting this healthier, cleaner lifestyle. Basically, I forgive myself for eating these foods because it’s planned and part of my diet plan and I’m rocking it on all the other days.
Generally, nutrients from food sources are more efficiently utilized by the body than isolated substances. For instance, fresh fruit and vegetable juice could be used to provide concentrated amounts of particular nutrients, such as vitamins A and C, to the diet. As another example, eating plenty of leafy green vegetables is a healthy option for those wishing to add calcium to the diet.
If you suspect that you have had a serious reaction from a dietary supplement, let your health care provider know. He or she may report your experience to the FDA. You may also submit a report to the FDA by calling 800-FDA-1088 or completing a form online. In addition, report your reaction to the dietary supplement company by using the contact information on the product label.