FDA regulations for nutritional supplements differ in important ways from those for prescription or over-the-counter drugs. For one thing, pharmaceutical companies have to gather data showing that a new drug is safe and effective in order to get the FDA's approval to market the drug. Makers of dietary supplements don't have to show that sort of proof. Be sure to let your doctor know about any nutritional supplement you plan on taking so you can discuss whether it's right for you and the appropriate dose.
The majority of adults in the United States take one or more dietary supplements either every day or occasionally. Today's dietary supplements include vitamins, minerals, herbals and botanicals, amino acids, enzymes, and many other products. Dietary supplements come in a variety of forms: traditional tablets, capsules, and powders, as well as drinks and energy bars. Popular supplements include vitamins D and E; minerals like calcium and iron; herbs such as echinacea and garlic; and specialty products like glucosamine, probiotics, and fish oils.
Because observational studies may not fully control for dietary factors, exercise habits, and other variables, they can't prove whether the treatment is responsible for the health benefits. "People who take supplements tend to be more health conscious, exercise more, eat healthier diets, and have a whole host of lifestyle factors that can be difficult to control for fully in the statistical models," Dr. Manson says.
Health care experts haven't reached a consensus on the issue of vitamin and mineral supplements. Many say that if you are healthy and eat a well-balanced diet, you don't need any. But not all of us eat a well-balanced diet. And sometimes, you may follow a nutritious diet and still be deficient. Many women fail to get the adequate amount of vitamins and minerals. Stress increases your need for vitamins and minerals, especially C, B-complex and zinc.
A visit to the health food store can be an overwhelming experience. It's tough to figure out what to choose from among the dizzying assortment of dietary and nutritional supplements on the shelf. From vitamins to minerals to weight loss pills, there are thousands of options to choose from. But do you really need any of them? Do they really work, and if so, which ones are best?
Reduced nutritional density in many foods, combined with the use of refined "foods" like sugar, white flour and refined oils, places a greater priority on eating the most nutritious foods. Farm produce grown organically generally has higher levels of essential nutrients such as trace minerals because the soil contains higher levels of trace minerals and the produce grows slower and thus has more time to absorb nutrients from the soil. Examples of nutrient dense foods are sardines, wild salmon, shellfish, eggs, liver, kale, collards and spinach, sea plants (seaweed), garlic, blueberries, and dark chocolate. 
Brain iron deficiency should be one of the first considerations when looking for a cause of restless legs syndrome (RLS). However, many doctors don’t know that iron deficiency is one cause of RLS, and therefore don’t test for it, particularly in men, in whom iron deficiency is uncommon. Diagnosing low brain iron is tricky, because doctors have to infer it from blood levels. Several tests are used to measure iron in the blood. The most important for diagnosing iron deficiency measures ferritin, the primary form of stored iron in the blood. (Locked) More »
Although the European Court of Justice's Advocate General subsequently said that the bloc's plan to tighten rules on the sale of vitamins and food supplements should be scrapped, he was eventually overruled by the European Court, which decided that the measures in question were necessary and appropriate for the purpose of protecting public health. ANH, however, interpreted the ban as applying only to synthetically produced supplements, and not to vitamins and minerals normally found in or consumed as part of the diet. Nevertheless, the European judges acknowledged the Advocate General's concerns, stating that there must be clear procedures to allow substances to be added to the permitted list based on scientific evidence. They also said that any refusal to add the product to the list must be open to challenge in the courts.
Nutritional supplements may be designed to provide specialized support for athletes. Some of these consist of high-protein products, such as amino acid supplements, while other products contain nutrients that support metabolism, energy, and athletic performance and recovery. People engaging in intense athletic activity may have increased needs for water-soluble vitamins, antioxidants, and certain minerals, including chromium. Sports drinks contain blends of electrolytes (salts) that the body loses during exertion and sweating, as well as vitamins, minerals, and performance-supporting herbs.