According to US & Canadian Dietary Reference Intake guidelines, the protein Recommended Dietary Allowance (RDA) for adults is based on 0.8 grams protein per kilogram body weight. The recommendation is for sedentary and lightly active people.[26][27][28] Scientific reviews can conclude that a high protein diet, when combined with exercise, will increase muscle mass and strength,[29][30][31] or conclude the opposite.[32] The International Olympic Committee recommends protein intake targets for both strength and endurance athletes at about 1.2-1.8 g/kg body mass per day.[22] One review proposed a maximum daily protein intake of approximately 25% of energy requirements, i.e., approximately 2.0 to 2.5 g/kg.[27]

For instance, foods rich in vitamin E and beta-carotene are healthy and can help reduce cancer risk. However, the U.S. Preventive Services Task Force (USPSTF) and the American Academy of Family Physicians (AAFP) recommend against taking vitamin E or beta-carotene for the prevention of cardiovascular disease. People who smoke or are at risk for lung cancer also should avoid beta-carotene. It can increase their risk of lung cancer.