In the United States, manufacturers of dietary supplements are required to demonstrate safety of their products before approval is granted for commerce. Despite this caution, numerous adverse effects have been reported, including muscle cramps, hair loss, joint pain, liver disease, and allergic reactions, with 29% of the adverse effects resulting in hospitalization, and 20% in serious injuries or illnesses. By more than five-fold, the highest incidence of health problems derived from "combination products", whereas supplements for vitamins and minerals, lipid products, and herbal products were less likely to cause adverse effects.
"These products provide a subtle, incremental effect. You can't use a sports supplement for a week and expect to gain pounds of muscle, but if used properly, research shows they can provide a slight, not overwhelming, edge," says Andrew Shoa, PhD, vice president for regulatory affairs for the Council for Responsible Nutrition, a trade association for the dietary supplement industry.
Vitamins can be natural or synthetic. Natural vitamins are extracted from food sources, while synthetic vitamins are formulated in laboratory processes. The only vitamin for which there is a noted difference between the natural and synthetic forms is vitamin E. The natural form is labeled d-alpha-tocopherol while the synthetic form is named dl-alpha-tocopherol, with the extra "l" signifying laboratory production. Natural vitamin E has been shown to be slightly more absorbable by the body than the synthetic version, although for other vitamins no significant differences in absorption have been noted.
If you do decide to diet, you still need to maintain good nutrition. You want to cut back on calories, not nutrients. And while you want to reduce fat, don't eliminate it entirely. Some studies suggest that older women who maintain a higher body-fat percentage are less likely to suffer from osteoporosis and other conditions associated with menopause. Fat cells also retain estrogen, which helps maintain the calcium in your bones. Younger women should be careful, too: a low body fat percentage can lead to infertility; below 17 percent may lead to missed periods, also known as amenorrhea.
Nutritional supplements are items that are usually considered non-food items that are used to enhance your nutritional program. Supplements may include, but are not limited to, vitamins, minerals, bars, and energy drinks or sports nutrition products to enhance performance. Supplements should be used alongside a healthy diet, but not replace it. To find a dietitian in your area that can assist you with supplements, go to www.eatright.org.
Studies link high sodium intake to higher blood pressure, and evidence suggests that many people at risk for high blood pressure can reduce their risk by consuming less salt or sodium, as well as following a healthy diet. Most Americans consume more sodium than they need. The recommended amount is less than 2,300 mg per day for children and adults to age 50. The limit drops to 1,500 mg per day for those 51 and older or those of any age who are African American or have hypertension, diabetes or chronic kidney disease. You get 2,300 mg in just one teaspoon of salt. One good way to reduce your sodium intake is to eat fewer prepared and packaged foods.
Overall diet is an important first consideration for those considering nutritional supplementation. Healthy dietary habits can help optimize nutrition and the absorption of supplements, and nutritional supplements cannot substitute for a diet that is not nutritionally balanced in the first place. Supplements are best used moderately to supply any extra nutritional requirements. Sound diets contain a variety of wholesome foods. At least five servings per day of fruits and vegetables are recommended, as well as the inclusion of whole grains in the diet. Variety in the diet is important to provide a full range of vitamins and minerals. Overeating inhibits digestion and absorption of nutrients, while regular exercise contributes to sound nutrition, by improving metabolism and digestion. Drinking plenty of clean water prevents dehydration, improves digestion, and helps the body flush out impurities.
Vitamin C protects the brain and nervous system from damage caused by stress because the synthesis and maintenance of chemical neurotransmitters such as adrenaline and noradrenaline requires adequate levels of vitamin C.  Vitamin C is also needed to repair collagen which is essential for skin, blood vessels, bones and joints, and muscles. When these are damaged by physical stress, extra vitamin C is necessary. A controlled trial of 91 adults who experienced increased anxiety and stress 2-3 months after an earthquake in New Zealand in 2011 was divided into three groups, two were given a broad spectrum supplement of micronutrients in low or higher doses.  The supplements were found to alleviate the experience of stress, with the biggest dose having the biggest effect.
"A smoothie with only fruits and fruit juice is essentially dessert!" Rebecca Lewis, in-house R.D. at HelloFresh, tell SELF. Smoothies can definitely be a healthy meal option, provided you're using vegetables in addition to those fruits, and high-protein, high-fiber ingredients like almond milk and chia seeds. Unfortunately a lot of smoothies (especially store-bought varieties) tend to pack in sugar. In fact, a small size at common smoothie stores like Jamba Juice can often contain more than 50 grams of sugar. To be sure you don't end up with a total gut bomb, consider making smoothies yourself. Or double check the ingredient list at your favorite shops and supermarkets.
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Now, the benefits of good nutrition are fairly obvious to most of us. You have more energy, your health improves, and your productivity blossoms. Healthy eating also plays a huge role in maintaining a healthy weight, which means a decreased risk of type 2 diabetes, certain cancers, heart problems, high blood pressure, and a host of other health ailments. (Genetics also plays a significant role. I'm not some crazy person who thinks genes don't matter.)
Trying to balance the demands of family and work or school—and coping with media pressure to look and eat a certain way—can make it difficult for any woman to maintain a healthy diet. But the right food can not only support your mood, boost your energy, and help you maintain a healthy weight, it can also be a huge support through the different stages in a woman’s life. Healthy food can help reduce PMS, boost fertility, make pregnancy and nursing easier, ease symptoms of menopause, and keep your bones strong. Whatever your age or situation, committing to a healthy, nutritious diet will help you look and feel your best and get the most out of life.
^ Dwyer, J. T; Wiemer, K. L; Dary, O; Keen, C. L; King, J. C; Miller, K. B; Philbert, M. A; Tarasuk, V; Taylor, C. L; Gaine, P. C; Jarvis, A. B; Bailey, R. L (2015). "Fortification and Health: Challenges and Opportunities". Advances in Nutrition: An International Review Journal. 6 (1): 124–131. doi:10.3945/an.114.007443. PMC 4288271. PMID 25593151.
The need for efficient detoxification and excretion is greatly increased by environmental pollution from the chemical industry, herbicides and pesticides used by industrial agriculture, antibiotic treatment of animals, transport, and plastic packaging.  In our polluted world, the increased toxic load may be compensated for by an increase in nutrients to promote detoxification. One can respond by taking large doses of supplements of essential nutrients, for example, antioxidants vitamin C and E, and an adequate dose of selenium, which help the body detoxify harmful chemicals. Also helpful is regularly taking sauna baths, fasting periodically, and eating an excellent diet that includes generous portions of dark green leafy vegetables and colorful vegetables and fruits. 
For example, while increased consumption of fruits and vegetables are related to decreases in mortality, cardiovascular diseases and cancers, supplementation with key factors found in fruits and vegetable, like antioxidants, vitamins, or minerals, do not help and some have been found to be harmful in some cases. In general as of 2016, robust clinical data is lacking, that shows that any kind of dietary supplementation does more good than harm for people who are healthy and eating a reasonable diet but there is clear data showing that dietary pattern and lifestyle choices are associated with health outcomes.