Most Americans get far more protein than they really need. In theory, that may not be wise. Like carbohydrates, protein provides 4 calories per gram, and excess calories from any source will be stored as body fat. Excess dietary protein increases calcium loss in the urine, perhaps raising the risk for osteoporosis ("thin bones," more a worry for women) and kidney stones (a particular worry for men).
A year later, a second Harvard study added to the concern. The Physicians' Health Study of 20,885 men did not evaluate diet per se, but it did measure the blood levels of ALA in 120 men who developed prostate cancer and compared them with the levels in 120 men who remained free of the disease. Men with moderately high ALA blood levels were 3.4 times more likely to develop prostate cancer than men with the lowest levels; curiously, though, men with the very highest levels were only 2 times more likely to get the disease.
Something else to remember: an estimated 90 to 95 percent of dieters who lose weight regain all or part of it within five years, and the consequences can be even worse than simply being overweight. Those who exercise regularly as part of a weight loss diet and maintenance program are more likely to keep the weight off. Also note that an overly restrictive diet can lead to more overeating, a natural reaction to food deprivation.
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The need for efficient detoxification and excretion is greatly increased by environmental pollution from the chemical industry, herbicides and pesticides used by industrial agriculture, antibiotic treatment of animals, transport, and plastic packaging.  In our polluted world, the increased toxic load may be compensated for by an increase in nutrients to promote detoxification. One can respond by taking large doses of supplements of essential nutrients, for example, antioxidants vitamin C and E, and an adequate dose of selenium, which help the body detoxify harmful chemicals. Also helpful is regularly taking sauna baths, fasting periodically, and eating an excellent diet that includes generous portions of dark green leafy vegetables and colorful vegetables and fruits. 
It's trendy to think "food should be fuel" or that food is something that helps you lose (or, ahem, gain) weight. But thinking only in terms of number on the scale takes away a huge part of what eating is about: pleasure. "If you think of eating as something enjoyable and something you do without guilt or without judging yourself, and you stay active, you're less likely to overeat, have a better diet, and maintain any weight loss for the long haul," says Zied. It's true: feeling guilty about your food choices can undermine weight loss—and even pack on the pounds—while a celebratory mindset gives you more control over your diet and can thwart weight gain, found a 2014 study in the journal Appetite.
Nutritional supplements may be designed to provide specialized support for athletes. Some of these consist of high-protein products, such as amino acid supplements, while other products contain nutrients that support metabolism, energy, and athletic performance and recovery. People engaging in intense athletic activity may have increased needs for water-soluble vitamins, antioxidants, and certain minerals, including chromium. Sports drinks contain blends of electrolytes (salts) that the body loses during exertion and sweating, as well as vitamins, minerals, and performance-supporting herbs.