“For example, prior studies have suggested that variants in CYP1A2, (a gene) encoding the enzyme responsible for more than 95 percent of caffeine metabolism, may alter associations of coffee drinking with cardiovascular-related outcomes, with slower caffeine metabolizers having higher risk of developing hypertension (high blood pressure) or having a myocardial infarction (heart attack) relative to their non-drinking counterparts, whereas faster caffeine metabolizers who drink coffee are at no or lower risk of these outcomes.”
In the Hungry For Change Book we discuss the addictive nature of caffeine and when consumed in large quantities, can lead to adrenal fatigue. Coffee is also a diuretic, meaning it purges water from your body. That said, if you want to function at a high level and remain well hydrated, then it would be a better choice to replace coffee with a natural alternative. The list below provides some great tasting substitutes.
Statistically, women who take four or more cups of coffee on a regular daily basis have a 25% reduced chance of falling scourge to this cancer compared to the women who drink less than one cup daily. On the same spectrum, researchers have found a relationship between frequent coffee drinking and lower rates of breast, colon, rectal, and liver cancers.
5-HIA, an organic acid and component of the neurotransmitter serotonin (the happy chemical) seen in the urine tends to be elevated in coffee drinkers, which means they may be at risk for lower levels of serotonin synthesis in the brain. Serotonin is necessary for normal sleep, bowel function, mood, and energy levels. It is a vicious cycle, as caffeine can disrupt sleep and promote anxiety and depression. We all know someone who tends to be tired, wired and over-caffeinated!
Do you drink your coffee first thing in the morning? You may want to think again.”Caffeine causes sugar to release into the bloodstream, creating a spike in insulin and a resulting drop in blood sugar,” says health coach and nutritionist Kristie Santana. “This will cause your body to require even more sugar, which will lead to food cravings.” Additionally, studies have found that drinking coffee first thing in the morning interferes with our bodies’ production of cortisol, which can increase your tolerance to caffeine and make you more reliant on the drink.
"Caffeine for treatment of Parkinson disease" Ronald B. Postuma, MD, MSc, Anthony E. Lang, MD, Renato P. Munhoz, MD, Katia Charland, PhD, Amelie Pelletier, PhD, Mariana Moscovich, MD, Luciane Filla, MD, Debora Zanatta, RPh, Silvia Rios Romenets, MD, Robert Altman, MD, Rosa Chuang, MD and Binit Shah, MD. doi:10.1212/WNL.0b013e318263570d August 1, 2012. Abstract. Accessed 15 December 2013. 

More recently, Australian researchers looked at 18 studies of nearly 458,000 people. They found a 7% drop in the odds of having type 2 diabetes for every additional cup of coffee drunk daily. There were similar risk reductions for decaf coffee drinkers and tea drinkers. But the researchers cautioned that data from some of the smaller studies they reviewed may be less reliable. So it's possible that they overestimated the strength of the link between heavy coffee drinking and diabetes.


If you’re working 80 hours a week, getting three hours of sleep a night, and have no energy because you’re living on carb-heavy takeout, drinking coffee non-stop during the day is a problem. It’s not the coffee; it’s the fact that you’re using the coffee as a crutch. Craving a steaming hot cup or two is fine, being totally dependent on coffee to function isn’t.
According to Jill Weisenberger, MS, RDN, CDE, one of the easiest ways to make sure your coffee is brewed in a healthy way is to consider how you’re filtering it. Those reusable filters might be tempting (and sure, provide less waste), but using recyclable paper filters has an added bonus for your nutrition. “Filtering coffee with paper removes two compounds, cafestol and kahweol, that raise both total and LDL cholesterol levels,” she explains. Here’s how coffee can help you learn.
Other studies have tried to tease apart which ingredients in coffee contribute to its health benefits. Those might include its antioxidants, which can combat cancer, and anti-inflammatory compounds, which can reduce the risk of chronic diseases such as heart conditions and even neurodegenerative disorders like Alzheimer’s, as well as the risk of liver diseases like cirrhosis and cancer.
Coffee doesn’t only help reduce the risk of developing melanoma—it does the same for basal cell carcinoma too, which affects millions of people every year. A 2012 study of 113,000 participants published by the American Association for Cancer Research found those who drank a minimum of three cups of coffee a day had a 20 percent lower risk of developing the skin cancer than those who didn’t.
Before you dismiss it as another internet myth, take a second to read on a bit. A study that involved over 37,000 individuals over 13 years was carried was recently finalised by leading cardiology researchers. Surprising enough, the research unearthed the fact that moderate coffee consumers had a 20 percent reduced danger of heart diseases compared to light or heavy drinkers, and nondrinkers.
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Cardamom is commonly used in Ayurvedic medicine, because it helps neutralize the stimulating effects of caffeine, but that’s not the only reason to add the spice to your java. A two-tablespoon serving has just 36 calories, is loaded with fiber, essential minerals, and cancer-fighting compounds; research published in the Asian Pacific Journal of Cancer Prevention found cardamom contains compounds with the potential to kill cancer cells and stunt new cancer cell growth. Cardamom has also been known to improve blood circulation in the body, help control cholesterol, cure dental diseases, and infections like gonorrhea. It’s even been said to cure impotency, erectile dysfunction, and premature ejaculation.
There are various theories on how coffee can help prevent or better yet, protect cognitive decline. But before that here is a quick fact, caffeine in coffee prevents beta-amyloid plaque build-up. The plaque can contribute to the beginning as well as the progression of Alzheimer’s. Besides, researchers theorise that since a regular cup of coffee can keep dietary diabetes away (a dementia risk factor), it can also be said to minimise the danger of developing dementia.
Sure, coffee isn’t going to do as much good as sunscreen when it comes to protecting your skin, but it still has some benefits. A 2014 study published by the American Association for Cancer Research found drinking coffee can help reduce the risk of melanoma, which according to the American Cancer Society causes a large majority of skin cancer-related deaths.

Research has revealed that regular coffee drinkers can reduce their risk of having a stroke. In women, it seems to lower the risk of heart diseases. It may increase your blood pressure temporarily, but that does not mean a stroke or heart disease is inevitable. It can often work to clear out the system and keep your heart functioning at an optimal level. A study also shows that coffee helps cure arrhythmias, which is abnormal heart rhythms.
Constituents in coffee can interfere with normal drug metabolism and detoxification in the liver, making it difficult to regulate the normal detoxification process in the liver. Another issue to be aware of with coffee intake is how certain medications such as levothyroxine (thyroid) as well as tricyclic antidepressants are poorly absorbed, making symptoms curiously worse for patients.
Malignant melanomas are the most dangerous and potentially life-threatening form of skin cancer and one of the most common cancer types in the United States. Studies have found that there is potentially as much as a 20 percent lower risk when a person drinks a minimum of four cups of coffee daily. The type of coffee matters here, as the study showed that decaffeinated coffee was not as effective. Studies on non-melanoma cancer and coffee have shown that people were 17 percent less likely to develop the most common form of skin cancer, basal cell carcinoma, if they drank three or more cups of coffee daily.
Coffee is one of the world’s most popular beverages for a reason: It not only tastes good and gives you a serious jolt of energy, but it also has plenty of amazing, body-boosting benefits. Which, in all honestly, is a major bonus considering the fact that most people are simply pleased to have something to help them get through their morning meetings. 
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